The elimination of sympathetic predominance by helium PP indicates the central role of CO(2) in establishing this phenomena. Considering this information and its other known advantages, helium should be considered for use during prolonged laparoscopic procedures for high-risk patients.

According to the World Health Organization (WHO) annually in the world traumatic brain injury (TBI) are about 10 million people, of whom 1.5 million die (9.0% of all causes of mortality), and another 2.4 million are disabled. The incidence of TBI is 1,8-5,4 per 100 thousand population, according to WHO, every year it increases by 2%. In Ukraine there is a TBI each year almost 100-200 thousand. Victims, about 1 million. Establish disability due to TBI. In 50-90% of patients after brain injury neurological symptoms persist or new emerging neurological syndromes that cause disability in 45% of them. Every year in Ukraine die from TBI 10-11 thousand citizens, in accordance mortality of 2.4 cases per 10 thousand population (USA- 1.8-2.2 per 10,000 per year).

Cardiovascular diseases (COD] occupy a leading place in the structure of general morbidity, primary disability and total mortality in Ukraine. Atherosclerosis is a systemic disease of the large and medium-sized arteries causing luminal narrowing (focal or diffuse) as a result of the accumulation of lipid and fibrous material between the intimal and medial layers of the vessel. Atherosclerosis involves an ongoing inflammatory response. Atherosclerosis leads to the formation of atherosclerotic plaques, which gradually increases in size and narrows the lumen of the vessel. Hypertension and atherosclerosis are the most common of the studied risk factors that lead to the development of stroke.