carried out on 50 patients with suspected adnexal masses from the department of Gynecology. The cases were recruited from Sri Venkateswara medical college, Tirupathi. All patients underwent ultrasound and the final diagnosis was made by histopathological examination in 50 cases. All histopathology reports were reviewed. The findings of sonography was correlated to histopathological findings, which were taken as gold standard. Results: In the present study out of 50 cases, 37 cases (74%) were diagnosed as benign in US, 13 cases (26%) were malignant on correlation to histopathological analysis. 40 cases (80%) were benign, 10 cases (20%) were malignant. 3 cases (6%) were assumed as malignant in US, but actually not in histopathology. The overall sensitivity was 92.5% and specificity was 100%, positive predictive value was 100% and negative predective value 76.92%. Conclusion: 2D US and Doppler study with a good equipment when appropriately performed by an experienced radiologist, using a proper methodology and standard guidelines has proved to be a very useful highly diagnostic and a reliable method with good sensitivity and specificity.