The article considers antibiotics of the quinolone series, their using and mechanism of action. Based on the literature data, their application, distribution mechanisms, accumulation and behavior in environmental objects are considered. It is noted that the role of aquatic plants in the processes of biochemical degradation has not been sufficiently studied. Under the conditions of a laboratory model experiment, we studied the patterns of ciprofloxacin elimination by hydatophytes, i.e., aquatic plants completely submerged in water (Canadian pondweed, rigid hornwort, Eurasian watermilfoil). The spectral characteristics of ciprofloxacin were studied and quantitative estimates of the absorption of the antibiotic from solutions with submerged aquatic plants were made. We calculated elimination rate constants and phytoremediation potential. It was found that the rate of elimination of ciprofloxacin and phytoremediation potential depended on the type of aquatic plant and the initial concentration of the antibiotic. The highest elimination rate was found in models containing hornwort. Based on the data obtained, a conclusion was made about the prospects for the using of hydatophytes in phytopurification systems for post-treatment of wastewater from ciprofloxacin.