The clusters with agro-industrial profile were developed within this scientific paper, based on a new conception of the capitalization of agricultural production at a regional level. In this approach "the agricultural farms" are more than basic links of the agro-industrial chain, they are the "essential links" without which "the chain" cannot serve as economic and social organization. The consumer has become the basic link of the chain, and in order to meet its requirements and options, the agro-industrial enterprises must come in a more effective way. The cluster proposed by this study must produce "what is required" and "how much is required" on the market. This agroindustrial chain highlights the cluster size (type, dimension and production capacity of goods), its chain links and the value added by this cluster. The overall objective of the "network enterprises" which constitute this agro-industrial cluster is to help its members to achieve increased production capacity and to be more profitable. A cluster model for enhancing grain production, integrated at regional level is proposed within this study.