Peer Review History: PLOS recognizes the benefits of transparency in the peer review process; therefore, we enable the publication of all of the content of peer review and author responses alongside final, published articles. The editorial history of this article is available here:

Purpose Our study aimed to analyze the characteristics of content word usage in mother's child-directed speech ( CDS) toward children with autism spectrum disorder compared to mother's CDS toward typically developing children. Method We analyzed the lexical characteristics of CDS of mothers of children with autism (16 dyads) and compared them from a language developmental perspective to mothers of 20 typical children at the same level of expressive language development. Results Results suggest that mothers of children with autism use equal amounts of content words at the same language level, but the content consists of significantly more concrete nouns and active verbs and rarely the use of abstract nouns, stative verbs, adjectives, and adverbs. Conclusion This study suggests that professionals and parents of children with autism should be aware of the importance of varying their language use of content words.

Virtual poster abstracts 46.9;94.1) for bilateral CL; 81.7% (95% CI 65.7;94.5) for bilateral CLP; 0% (0/5) for median CL; 66.7% (2/3) for median CLP; and 4.2% for CP (95% CI 1.4;6.6). Conclusions: The DR of CL(P) has increased in Denmark from 2009 to 2018. The DR of CLP is high, with the highest DR in bilateral CLP. However, the prenatal detection of cleft palate remains a challenge. VP10.03Atraumatic isolated fetal femur fracture: an unusual sonographic finding, diagnostic considerations and literature review

Wormian bones are isolated ectopic bones located in cranial sutures and fontanelles. The underlying pathogenesis of their formation is unknown. They have been found to be associated with craniosynostosis, osteogenesis imperfecta, genetic syndromes and head trauma; they can also be a normal variant. 1e12 This finding has been scarcely described in fetuses, 13,14 which precludes appropriate prenatal counseling.This study aimed to determine the short-and long-term outcomes in fetuses diagnosed with Wormian bones.