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A parasitological mapping of urinary schistosomiasis using filtration method was conducted in Biase and Yakurr LGAs of Cross River State, Nigeria by the Neglected Tropical Diseases Control unit in collaboration with the schistosomiasis/soil transmitted helminths unit of the Federal Ministry of Health, Nigeria in November 2012. The results of the study revealed a mean urinary schistosomiasis prevalence of 49% for the six schools under study in Biase and 30% for the six schools under study in Yakurr LGA. The mean ova load was 0.9 for males and 0.8 for females in the two LGAs. Integrated control measures put in place, included chemotherapy of infected individuals with praziquantel and health education on the predisposing factors responsible for the transmission of urinary schistosomiasis. An evaluation of the interventions was carried out in November 2014, after two rounds of treatment with Praziquantel and intensive education were given. Urine samples were collected from 600 school children, 300 from each of the two LGAs. The evaluation study using the urine filtration technique revealed a mean schistosomiasis prevalence of 0% for the six schools under study in Biase and 0.02% for the six schools under study in Yakurr LGA with mean ova load reduced to 0.3 for males and 0 for females in the two LGAs. Data analysis with SPSS package revealed a 100% participation of all selected school children in 12 schools (6 in each LGA). Statistical analysis showed that there was no significant difference in the prevalence between male and female (p>0.005). A student t-test showed a significant difference between prevalence rates in 2012 and the results in 2014 (p>0.005). The spatial distribution showed that endemic schools were distributed within marshy areas where rice was cultivated in the two LGAs. These results showed that with wide scale integrated control measures, urinary schistosomiasis can be eliminated or reduced to a disease of no public health importance.

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