Background: There have been significant advancements in contact lens designs and materials over the past few decades, the lenses still represent a foreign body in the ocular environment and may lead to physiological (corneal oedema or thinning) as well as mechanical (on corneal curvature) effects on the eye.As there are not many studies reporting the effect of contact lens on eyes in Indian population, this study was designed tofill the lacunae of knowledge in this context.Aims and Objective: To evaluate and compare the change in anterior central corneal curvature & central corneal thickness following use of soft contact lens (silicon-hydrogel) and Rigid Gas Permeable (fluoropolymer) contact lens.Materials and Methods: It was a Prospective, Observational, Comparative study Conducted at Venu Eye Institute & Research Centre, New Delhi. Forty eyes of 21 subjects who required contact lens were included in two groups: 20 eyes in group A (RGP contact lens users) and 20 eyes in group B (Soft contact lens users). A “baseline” parameters was measured prior to contact lens use & changes associated with contact lens wear was considered in relation to the normal baseline parameters when followed up at 3 and 6 months.Results: The Change in anterior central corneal curvature in both the groups was NOT statistically significant (p-value of >0.05) between pre-contact lens wear and with contact lens wear at 3 & 6 months. And, there was Significant Corneal thinning between pre-contact lens wear and with contact lens wear at 3 & 6 months in both the groups individually (p-value <0.05). However, on comparing the difference in change in CCT between both the groups was NOT statistically significant at 3 and 6 months.Conclusions: With contact lens use, there was no significant change in Anterior Central Corneal Curvature in Soft as well as RGP contact lens group at 3 & 6 months. Though there was significant central corneal thinning in both the groups individually at 3 & 6 months, However, on comparing the change in CCT between both the groups at 3 and 6 months was NOT significant.Asian Journal of Medical Sciences Vol.8(5) 2017 70-74

A B S T R A C T ORIGINAL ARTICLE ASIAN JOURNAL OF MEDICAL SCIENCESBackground: Nd: YAG laser is non-invasive and effective means to deal with the posterior capsule opacification. However safe it may have some inherent complications. Rise of intraocular pressure is frequently encountered and incompletely understood complication of YAG laser capsulotomy and documented with conflicting results. Aims and Objective: To assess the efficacy of Nd: YAG laser capsulotomy in term of visual outcome(Best Corrected Visual Acuity) and also study the changes in IOP after the procedure. Materials and Methods: Study evaluated the changes in IOP and visual acuity after Nd-YAG laser capsulotomy in 100 eyes with significant PCO after uncomplicated cataract surgery with IOL implantation. Complete ocular examination including visual acuity, anterior segment examination with slit lamp, fundus and applanation tonometry were performed pre and post-laser in all cases. Posterior capsulotomy was done with VISULAS YAG III Q-switched Nd: YAG laser machine by ZEISS. IOP was recorded before and then at 1hour, 1 Day, 1 week and 1 month post-laser in order to determine the IOP changes. Results: Pre-laser visual acuity ranged from 1/60 to 6/12. Results showed statistically significant improvement in BCVA with 70% patients had BCVA 6/6, 21% had BCVA 6/9 and 8% having BCVA 6/12 post-laser at 1 month. It was observed that 36% of the patients showed no change in IOP while 64% patients showed elevated IOP. Among these 59% patients show rise in IOP that was ≤5 mm Hg while only 5% of the patients had a rise of more than IOP >5 mm Hg. Most of these patients achieved their baseline IOP within 1 day and only 7 % patient had rise in IOP compared to baseline IOP on day 1. None of the patients show elevated IOP after 1 week. Conclusion: Our study showed that Nd: YAG laser posterior capsulotomy provided excellent results in terms of visual improvement and most of the patients had a rise of <5mm Hg which was transient in nature and routine antiglaucoma medication may not be needed in all the patient undergoing Nd:YAG capsulotomy, however caution should be exercised in glaucomatous, aphakic, high myopic and other high risk patients.