The article shows the results of non-destructive technological control of the defects number in the enamel insulated wire based on polyimide insulation. The application of statistical analysis of the control indicators measurement results with the help of a mathematical trend model for their use in insulation defects online control is considered. Recommendations for the practical use of the trend function parameters for processing the obtained measurement indicators are offered. The main parameters of the trend are run-in and the period of normal isolation during technological time. Theoretically shown and confirmed by measurements, the algorithm for quantitative assessment of the tendency of enamel insulation defects change for PEEIDH2-200 wire with two-layer polyimide insulation during the inline technological cycle. The algorithm allows for making technical decisions both in real time and remote analysis. Data on the sensitivity of this approach to technological changes are given.