Purpose is to identify process engineering of mining under the Late Bronze age (18th-13th centuries BCE) in the context of copper deposits in the Eastern Ukraine. Among other things, it concerns analysis of manufacturing artifacts (i.e. ore production and preparation) in Kartamysh archeological area within the copper-ore territory of Bakhmut basin of Donbas. Methods. Following methods have been applied: a comparative historical method supported by typological archaeological approach; statistical procedures; engineering and geological methods to determine extraction volumes and evaluate copper ore extraction from the mines in Kartamysh archaeological area as well as structural and technologic analysis; functional and typological analysis; traceological analysis; experimental modelling; and carbon dating. Findings. Analysis of the specialized mining artifacts in Kartamysh archaeological area as well as mining artifacts within other copper-ore deposits in Bakhmut basin, extracted actively under the Late Bronze age, has made it possible to consider newly a number of important issues connected with process engineering of mining, specialization and labour division of ancient miners as well as evaluate significance of Donbas copper mines for the system of metal production development in the Eastern Europe of the second millennium BCE. Originality.Analysis of Kartamysh archaeological area, where the majority of business performance objects are connected with mining, has helped the authors consider specialization of the industrial systems (i.e. different-purpose mine workings, various mining tools, and areas to prepare ore) right from the viewpoint of the production method. Since similar situation is typical for other Donets complex artifacts, being involved in scientific terminology as the mining and smelting one, it would be more reasonable to represent it as Donets ore mining system owing to its specialization in the integrated copper ore extraction and preparation. Practical implications.The research results develop the history of mining science and engineering inclusive of ancient mining history in the Eastern Ukraine. They may be applied to train mining experts and in the process of creation of museum exhibitions (looking ahead, creation of Kartamysh skansen) while synthesizing technical and humanitarian aspects of engineering activities.