The article considers the conditions for the sustainability of economic socialization of the entrepreneurship of rural areas of Ukraine. The main methods used in the study were clustering method, structural analysis, methods of economic evaluation of economic activity, financial condition of entrepreneurs taking into account in-dustry specifics and classification of business entities as large, medium and small enterprises. It is proved that the social mission of entrepreneurship of rural areas in the economic plane of estimates should be considered according to the concept of determining benefits and costs. The method of estimating the social price of pro-duction, which is a motivating factor for increasing wages in rural areas, is deter-mined. The trend of development of social and economic efficiency of enterprises in the formation of entrepreneurship of rural areas on average for one region of Ukraine and in the country as a whole is analyzed. It is proven that the realization of the entrepreneurship of rural areas within one region of Steppe, Forest-Steppe, Polissya and Western zones of Ukraine has a significant impact on people's well-being, quality and security of life, the amount of obligations to the subjects of in-terest and system of relations between entrepreneurs in agriculture.