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The goal of the present research is to investigate and analyze possible peculiarities of the psychological state of cancer patients undergoing treatment. Scores characterizing the trait and state anxiety were acquired using the Integrative Anxiety Test from four groups: adults with no appreciable disease, pregnant women, cancer patients examined during the specific antitumor treatment, and cancer patients brought into lasting clinical remission. Statistical analysis of the testing results revealed the bimodal type of the distribution of scores. The only statistically significant exception was the distribution of the state anxiety scores in cancer patients undergoing treatment that was clearly unimodal.

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There are presented the main principles and possibilities of simultaneous chemoradiotherapy, including intra-tumoral administration of antitumor drugs in combination with irradiation of primary bone tumors with soft tissue components, metastatic damage of bones, soft tissue tumors as well as superficial tumors and metastases. On the example of 23 patients the high efficiency of synchronous combined therapy is showed. The possibility of using low total doses of ionizing radiation in order to significantly increase the local cytotoxicity of antitumor drugs directly in the tumor focus is substantiated. The proposed variant of synchronous combined therapy makes it possible to obtain a pronounced local effect with minimal systemic toxicity.