In the analysis of the project documentation of a two-storeyed sports complex it was established that despite compliance of the project to all standards in the fire safety field, under certain conditions there is a danger of a delay of full people evacuation from the gym room in case of fire that can entail people’s death. For the purpose of ensuring fire safety several versions of space-planning decisions were considered. The scientific literature analysis showed efficiency of game theory use in the field of fire safety, however in the field of fire safety in construction it was not applied yet. Game theory Application (games with the nature in the conditions of uncertainty) for the revealed problem solution was proved. Three possible scenarios of emergence and development of the fire and four alternative space-planning decisions were considered. For all development scenarios of the fire time of critical values achievement of dangerous fire factors was defined. All necessary evacuation schemes are made and calculations are executed. On the calculated parameters basis the payoff matrix was constructed. An optimal variant of space-planning decisions was chosen. Research results showed expediency and efficiency of game theory application in the field of fire safety in construction.