Speleotherapy-is the method of treatment in conditions of mines and karst caves microclimate. At 40-50-th this method have begun to develop in Germany, Austria and Italy. Later at the 60-th years speleotherapy was put in to practice in East Europe (Poland, Hungary, Slovakia, Romania). The high efficiency of this method of treatment at bronchial asthma (BA) patients is proved. However, there are technical reasons and medical contraindications, which do not give opportunities to some patients to be put down in underground department. Therefore, the apparatus, which enables to create an highdispersed aerosol of rock salt (haloaerosol) on the surface of the ground was worked out. The method of haloaerosoltherapy with the use of highdispersed aerosol of rock salt is successfully applied in Ukraine about 20 years. More than 10 years one regimen of treatment was applied in all patients. The course of treatment lasted 24 days and included 21-22 seanses of haloaerosoltherapy during 60minutes everyone. However, new economic conditions dictate necessity of improvement and reconsideration of some well-known methods of treatment on the basis of new data about bronchoobstruction mechanisms and new technical decisions. The way to increase the effectiveness of patients treatment in conditions of rock salt aerosol medium is the development of technologies, which allow to receive an aerosol of the given concentration and dispersion with the purpose of needed influence on various levels of the respiratory tract.
64 psoriasis patients with moderate to severe form of the disease in its stationary stage and associated pathology of main excretory and detoxification systems were investigated. All patients were treated according to two medical complexes (MC). 32 patients were treated according to MC-1, which included sulphide mud applications at temperatures 42 0 C for 10-30 minutes; artificial brine baths of sodium chloride concentration of 60-120 g/l at a temperature of 38 0 C for 10-30 minutes; artificial ultraviolet irradiation up to 2 biodoses and daily (except Sunday) sessions of haloaerosoltherapy (artificial analogy of salt mine's aerosol) lasting 60 minutes. The treatment duration was 3 weeks. Another group of patients (32 persons) received MC-2. This complex included procedures, according to MC-1, completed with additional internal use of carbonic middle-mineralised boric bicarbonate sodium mineral water Luzhanskaya-7 (the type of Vichy) with the aim of detoxification.It was found that complex recovery treatment based on non-medicinal factorsphotobalneotherapy and haloaerosoltherapy (MC-1) has a positive effect on the clinical symptoms of psoriasis and immune status of patients. These positive changes were testified by the corresponding change in the PASI-index (Psoriasis Area and Severity Index), ∆PASI and dynamics of some immunological parameters. At the same time more pronounced positive dynamics of cutaneous manifestations of psoriasis and higher percent of patients with significant improvement by the end of treatment was achieved under the influence of MC-2. In addition, normalization of the neutrophils' absorbtive capasity by the level of PhAN (phagocytic activity of neutrophils -percentage of neutrophils wich ingurgitate latex) and certain improvement of their oxygen-dependent metabolism was observed under the influence of MC-2. The level of CD3 + -CD8 + -lymphocytes had also a tendency to increase in the group of patients who received MC-2 in with contradiction to MC-1. A significant decrease of Blymphocytes level was also observed in this group of patients. The higher indirect imunorehabilitative effect of MC-2 including mineral water Luzhanskaya-7 intake enriched with sulfates may be conditioned by the corrective influence of mineral water on the functional digestive and urinary disorders, reduction of endogenous intoxication manifestations and antigens flow from the gastrointestinal tract to lymphoid follicles.Conclusion: The received data testified the expediency of non-medicinal supplementation of rehabilitation treatment of psoriasis patients by internal use of bicarbonate sodium mineral water in case of associated pathology and more severe immunological disorders.
Aim: Investigation of the peculiarities of different haloaerosoltherapy regimes influence (treatment with different intensity of haloaerosol load) upon non-specific defense and cellular immunity at convalescents after community acquired pneumonia.Objectives: patients with community acquired pneumonia in the early convalescence period (after completing antibiotic therapy), who received treatment in conditions of artificial rock salt aerosol medium (haloaerosoltherapy).Material and Methods. 42 patients with non-severe community acquired pneumonia were examined in the early convalescence period before and after the course of haloaerosoltherapy, which was prescribed after antibacterial therapy. Immunological studies included: evaluation of phagocytic activity of neutrophils (PhAN -the percentage of phagocytic neutrophils), phagocytic number (PhN -average number of latex particles absorbed by a neutrophil); metabolism of neutrophils in the test with nitroblue tetrasolium (NBT-test) spontaneous and induced, which allowed to assess the functional reserve of neutrophils (FR); calculation of cytochemical coefficient (CCC) for lysosomal cationic proteins (LCP) and for myeloperoxidase (MPO) of neutrophils; number of T-and B-lymphocytes and their subpopulations (CD3 + -, CD4 + -, CD8 + -, CD22 + -lymphocytes), calculation the number of 0-lymphocytes and the ratio of CD4 + /CD8 + lymphocytes. Laboratory examinations were also conducted in 21 practically healthy individuals (control group).Two regimes of haloaerosoltherapy were used in recovery treatment of patients with community acquired pneumonia: treating complex №1 (TC-1) with standard haloaerosol load and with increased haloaerosol load (TC-2).Results. After completion the antibiotic therapy at patients with community acquired pneumonia the moderate inhibition of phagocytic activity of neutrophils (47,6±0,58% to 55,5±1,14% in control group) remained and was accompanied with a decrease in neutrophil bactericidal capacity, mainly oxygen-dependent. However, the disturbances of cellular immunity was observed which manifested by reduced number of T-lymphocytes, mainly on account of Thelper cells and decrease of the CD4 + /CD8 + ratio and was accompanied by the elevation of 0-lymphocytes percentage.Under the influence of recovery treatment on the base of haloerosoltherapy usage the positive dynamics of studied parameters was observed and it was more expressed when using treatment procedures with increased haloaerosol load. Conclusions.1. The patients with non-severe community acquired pneumonia have moderate disturbances of neutrophils phagocytosis, associated with secondary T-cell dysfunction, which are accompanied with the increasing in the number of undifferentiated 0-lymphocytes and B lymphocytes, which remained after of completing of antibiotic therapy. These changes determine the necessity of recovery treatment in this stage of the disease.2. Haloaerosoltherapy usage in the recovery treatment of convalescents after community acquired pneumonia improves the func...
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