Overall, aqueous extract of H. sabdariffa palliates insulin resistance, hyperglycemia, dyslipidemia and oxidative rout in high-fructose-induced metabolic syndrome rats.

No abstract

No abstract

Proximate composition, phytochemical and mineral composition of young and mature Polyalthia longifolia Sonn. leaves were investigated using standard analytical procedures. Young leaves of Polyalthia longifolia contained 9% protein, 4% ash, 0.21% lipid, 25% fibre, 8% moisture and 54% carbohydrate while the mature leaves contained 10% protein, 5% ash, 0.26% lipid, 19% fibre, 9% moisture and 57% carbohydrates. The results for the quantitative phytochemicals revealed that the young leaves contained 3.91 (ppm) tannins, 0.34 (ppm) phenols and 62% flavonoids with the mature samples showing a relative result of 3.69 (ppm) tannins, 0.33 (ppm) phenols and 63% flavonoids. The mineral analysis of both samples showed that they contained appreciable quantities of minerals with the mature sample having higher concentrations of Na (30.03 mg/100 g), K (23.55 mg/100 g), Ca (89.18 mg/100 g) and Mg (27.55 mg/100 g) relative to Na (20.30 mg/100 g), K (16.93 mg/100 g), Ca (57.03 mg/100 g) and Mg (14.48 mg/100 g) found in the young leaves. The study showed that the leaves examined contained high levels of carbohydrates and fibre, low fat and phenols but very rich in minerals. These findings suggest that the leaves of Polyalthia longifolia might be a potential source of carbohydrates, fibre, phytochemicals and mineral elements for human and animal use.

This study showed that Obiolor extenuated high-fat diet-mediated dyslipidaemia, protein oxidation, lipid peroxidation and DNA fragmentation in rats.