Fifty blood samples were collected from sheep of different regions in Salah Al-Din Governorate for the period from November 2019 to April 2020 to detected some hematological and biochemical criteria and the infection with intestinal protozoa (Eimeria, Cryptosporidium) and helminthes (Marshallagia sp, Trichostrongylus sp, Ostertagia sp ,Haemonchus sp, Chabertia sp , Nematodirus sp , Toxocara sp, Cooperia sp , Oesophagostomum sp , Strongyloid sp) . The results of the study showed that the infection with intestinal protozoa and nematodes in sheep had an effect on the haematological parameters, as there was a significant decrease in the red blood cells (RBCs), volume of packed blood cells (PCV), lymphocytes compared to the control Groups reaching 4.9±1.173,21.9±7.2±1.871, 21.9± 2.881, 45.1± 3.624 respectively. While there was a significant increase in the number of white blood cells (WBCs) compared to the control groups reaching 13.2±3.116 respectively. Regarding biochemical parameters, there was a significant decrease in the concentration of protein and albumin, 5.308±0.552, 2.124±0.372 respectively, as well as a significant decrease in the concentration of iron and calcium, 158.6 ± 34.4, 8.73± 2.48 respectively, while no change in the concertation of magnesium and potassium was reported.

This study was designed to diagnose intestinal protozoans and Nematodes in sheep in Salah al-Din Governorate, As 500 sheep fecal samples were collected from different regions of Salah Al-Din Governorate for the period from November 2019 to April 2020, The result of the study showed that the total number of positive samples for infection with intestinal protozoa and Nematodes is 270 samples with an infection rate of (54%), and The results also showed that the total infection rate of intestinal protozoa was (24%), Nine species of Eimeria were diagnosed in sheep, and the highest infection rate for E. parva (14.4%) and the lowest rate for E. weybridgensis (2.2%), While Cryptosporidium Spp the infection rate was (1.8%).  As for overall infection of nematodes was (42%) The highest rate of infection  Marshallagia marshalli was (44.4%) and the lowest rate of infection with Strongyloides papillosus was (2.9%). The diagnosis of oocysts and eggs depended on the morphological features and measurments that existing in specialized  reference.