Objectives: We aimed to develop and validate a mental health stigma measurement tool for use within the social media context, utilizing the tool to assess whether the stigma shown in face-to-face interactions translates to social media, coupled with comparing whether social media use can cause the stigma among a sample of Middle Eastern and Western populations. Methods: The development and validation phase comprised a systematic process that was used to develop an assessment tool that could be used within the social media context and establish its validity and reliability. A 5-point Likert-type scale (1 = strongly disagree to 5 = strongly agree) was developed to assess mental health stigma. The anonymous questionnaire was distributed from June 2022 to August 2022 on various social media platforms and groups predominated by the two demographics of interest, enrolling 1328 participants (with only 1001 responses deemed valid). The utilization phase consisted of bivariate and multivariable analysis of the data. The cutoff points for low, medium, and high scores were the 25th, 50th, and 75th percentil, respectively. Results: The instrument comprised three dimensions: acceptance, intolerance, and digital care sentiment. In the Middle Eastern subset of participants, a higher score of intolerance (more stigma) toward mental illness was found in 72.4% of the participants, with a higher score of acceptance being 35.1% and of digital care sentiment being 46.4%. The mean scores for all the scales were as follows: intolerance (3.08 ± 0.64), acceptance (3.87 ± 0.71), and digital care sentiment (3.18 ± 0.69). For Westerners, a higher score of intolerance toward mental illness was found in 24.0% of the participants, with a higher score of acceptance being 56.8% and of digital care sentiment being 38.2%. The mean scores for all the scales were as follows: intolerance (2.28 ± 0.73), acceptance (4.21 ± 0.61), and digital care sentiment (3.08 ± 0.62). Various results were obtained regarding the effect of individual social media platforms on the different subscales. Conclusions: Stigma does follow people on social media, whether they are Middle Easterners or Westerners, although to varying degrees. The results of social media interaction and activity varied based on the group that used them, with some having an impact on one group but not the other. For these reasons, proper guidance is advised when utilizing and interacting with social media platforms.

Antimicrobial resistance poses a significant threat to global health, amplified by factors such as water scarcity and suboptimal hygienic practices. Addressing AMR effectively necessitates a comprehensive strategy encompassing enhanced access to potable water, developing innovative antibiotics, and exploring alternative treatment modalities, such as harnessing solar photocatalysis with zinc oxide nanoparticles for water purification and antimicrobial applications. The Laser-Assisted Chemical Bath Synthesis (LACBS) technique facilitates the fabrication of pure ZnO nanostructures, providing a potentially efficacious solution for mitigating pathogen proliferation and managing wastewater. The photocatalytic degradation of MB and MO dyes was investigated using blue laser light at 445 nm, and degradation rates were determined accordingly. Ag-doped ZnO nanostructures were characterized through X-ray diffraction, field emission scanning electron microscopy, energy dispersive X-ray spectroscopy, and Fourier-transform infrared spectroscopy. The antimicrobial efficacy of LACBS-synthesized ZnO nanoparticles was assessed against C. albicans, S. aureus, B. subtilis, E. coli, and K. pneumoniae using the disc diffusion method, revealing 40 mm, 37 mm, 21 mm, 27 mm, and 45 mm inhibition zones at the highest concentration of doped-Ag (4.5%), respectively. These inhibition zones were measured in accordance with the guidelines established by the Clinical and Laboratory Standards Institute. X-ray diffraction patterns for ZnO, ZnOAg(1.5%), ZnO:Ag(3%), and ZnO:Ag(4.5%) samples revealed variations in intensity and crystallinity. Scanning electron microscopy exposed morphological disparities among the nanostructures, while energy-dispersive X-ray spectroscopy verified their elemental compositions. UV-Vis absorption analyses inspected the optical band gaps, and Fourier-transform infrared spectra identified the stretching mode of metal-oxygen bonds. Under blue laser irradiation, Ag-doped ZnO exhibited enhanced photocatalytic activity during the photocatalytic degradation. These nanoparticles, synthesized via the cost-effective and straightforward LACBS method, benefit from silver doping that augments their electron-trapping properties and photocatalytic activity, thereby enabling efficient dye degradation. Consequently, Ag-doped ZnO nanoparticles hold promise as a potent solution for counteracting drug-resistant microorganisms and as an effective disinfectant.