OctaplasLG is indicated for use in patients undergoing cardiac surgery who require replacement of multiple clotting factors. The use of OctaplasLG over single-donor fresh frozen plasma (FFP) may have beneficial effects when considering the transmission of enveloped viruses. Additionally, it has the potential for fewer adverse reactions, reduced disease transmission, and a more homogenous coagulation factor composition. However, its efficacy and safety have not yet been evaluated in the pediatric population. Pediatric patients aged less than 2 years old and less than 10 kg, who underwent complete tetralogy of Fallot repair and received either OctaplasLG or FFP intraoperatively were identified over a 10-year period for this retrospective analysis. A review of case notes, intra-operative, and laboratory data were used to assess intraoperative blood product usage, blood loss, and postoperative coagulopathy. Data were analyzed to assess the efficacy of OctaplasLG in achieving hemostasis when compared to FFP. Results showed clinically better hemostasis postoperatively in OctaplasLG group compared with FFP group and better coagulation results. OctaplasLG was as effective as FFP when used in pediatric patients undergoing cardiac surgery.

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Background: Different diagnostic definition and criteria have been recommended by different expert groups for the diagnosis of metabolic syndrome, however, it’s prevalence in the same population could differ depending on the definition used yielding different results. In Iraq, there is a lack of research comparing these different diagnostic definitions. Objective: To find out the most suitable metabolic syndrome definition to be used for Iraqi people.  Methods: 320 participants were recruited for this study, 53.4% men and 46.6% women, aged between 25-85 years, visiting Baghdad Teaching Hospital, the prevalence of metabolic syndrome according to different definitions were compared and the agreement was assessed by the Kappa statistic. Results: Metabolic syndrome was diagnosed in 37.8%, 40.6% and 46.9% participants respectively for the National Cholesterol Education Programme Adult Treatment Panel III 2005, International Diabetes Federation 2005 and the recently (2009) revised International Diabetes Federation definition. The prevalence was higher in women than in men, independent of the criteria used. The Kappa statistics suggested that the agreement between the three definitions ranged from good-to-very good, Conclusion: Metabolic syndrome was high in this Iraqi cohort regardless of the definition used. The recently (2009) revised International Diabetes Federation definition may be more suitable in diagnosis of metabolic syndrome in Iraq.

BACKGROUND: Nebulized Salbutamol have great advantages for patients with respiratory problems by depositing drugs directly to the lungs, inspite of reported adverse metabolic effects on different electrolytes and glucose heamostasis of patients.AIM OF STUDY: To evaluate the effect of nebulized salbutamol used in the management of patients with asthma who have normal serum potassium and blood glucose levels. in the emergency department after 30 and 60 minutes of administration and to find out if these results are of clinical importance that should be taken in consideration when treating patients especially those with abnormal glucose hemostasis or electrolyte disturbance. PATIENTS & METHODS: The study is a prospective follow up study conducted in Emergency Department of Baghdad Teaching Hospital through the period from 1st of April, 2017, to 31st of January, 2018 on a sample of 100 patients. After administration of nebulized salbutamol, the Potassium and Glucose levels of patients were assessed in three periods; baseline, after 30 minutes and after one hour.RESULTS: The potassium mean was significantly decreased after 1 hour of nebulizer administration (p<0.001). The random blood sugar mean was significantly increased after 1 hour of nebulizer administration (p<0.001). The potassium level was significantly decreased one hour after nebulizer administration for patients with negative steroids history (p=0.03), while no significant difference in potassium level was observed for patients with positive steroids history.CONCLUSIONS: The nebulizer applying salbutamol has a profound effect in lowering the Potassium level and increasing blood glucose level after 60 minutes of administration.

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