Purpose: To evaluate early changes in anterior segment parameters by Scheimp ug-Placido disc topography system and changes in retinal layers by optical coherence tomography in primary angleclosure suspects after laser peripheral iridotomy Methods: One eye of 26 patients with primary angle closure suspect and of 20 healthy subjects were included in this retrospective cross-sectional study. Anterior chamber depth/volume, iridocorneal angle and central corneal thickness were obtained by Scheimp ug-Placido disc topography system. Retinal thickness, retinal nerve ber layer thickness and ganglion cell-inner plexiform layer thickness were acquired by optical coherence tomography. All the tests were repeated 1 week and 1 month after laser peripheral iridotomy.Results: The mean ages of the patients and healthy controls were 64.8±10.7 years and 64.5 ± 3.9 years, respectively (p=0.990). Anterior chamber depth/volume and iricorneal angle value were lower in the PACS group (p<0.001, for all). Anterior chamber volume and iridocorneal angle increased signi cantly after laser peripheral iridotomy (p=0.004, for both). While foveal thickness decreased signi cantly after laser peripheral iridotomy (p=0.027), retinal nerve ber layer thickness increased in superior and temporal quadrants (p=0.038 and p=0.016, respectively). Conclusion: Our results suggest that LPI in patients with PACS provides improved retinal thickness and RNFL thickness, as well as anterior chamber parameters.

Rectal neuroendocrine carcinomas constitute <1% of all neuroendocrine carcinomas and <1% of all gastrointestinal tract malignancies. Cutaneous metastases of rectal neuroendocrine carcinoma are rarer than visceral metastases. We represent a 71-year-old man who was diagnosed with neuroendocrine tumor grade 3 originating from the rectum 1 year ago. He was referred for 18 F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography for restaging after 6 cycles of chemotherapy and radiotherapy. Intensely increased 18 F-FDG uptake in the right cutaneous inguinal region was consistent with neuroendocrine carcinoma metastasis with biopsy from the same region.

Neuroendocrine tumors are slow-growing tumors originating from neuroendocrine cells and capable of metastasis. Most of them are found in the gastrointestinal tract; however, they can also be rarely seen in other organs. Testicular neuroendocrine tumors account for less than 1% of all testicular neoplasms. They may present as primary testicular or secondary tumors from extratesticular sources. Jejunal neuroendocrine tumor metastasis to the testis is extremely rare. We present the case of a 61-year-old man with a jejunal neuroendocrine tumor and metastases to bilateral testicles revealed on Gallium-68-DOTATATE positron emission tomography/computed tomography.

Objectives: Renal cell carcinoma (RCC) comprises 85%-90% of primary renal malignant tumors originating from the renal tubular epithelium and has different genetic characteristics. This study aimed to investigate the potential predictive role of 18 F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography (PET/CT) and metabolic parameters in overall survival (OS) analysis in patients with RCC. Methods: 18 F-FDG PET/CT images of 100 patients performed for initial staging before surgical or oncological treatments were analyzed retrospectively. Maximum standard uptake value (SUV max -T) of the primary tumor was calculated and its relationship to patient survival was analyzed. The median follow-up time was 5.61 years (0.01-8.7 years). Results: SUV max -T levels in the patients ranged from 2.1 to 48.9 (median 5.9, mean 9.0±7.9). SUV max -T was significantly higher in RCC-related death more positive than in the negative cases (p<0.001). However, there was not any statistical significance for gender and pathological subtypes on the survival outcomes of patients (p=0.264 and p=0.784). The patients’ 1-year, 3-year, and 5-year OS rates were 71%, 61%, and 57%, respectively. The highest action of SUV max -T for estimating OS was a cut-off level of 5.4, which maintained sensitivity and specificity of 81% and 75%, respectively. However, cancer staging remained independent significance for OS (p<0.001). Conclusion: SUV max of primary tumor and cancer stage were demonstrated as significant prognostic factors for OS in patients with RCC. Evaluation of 18F-FDG accumulation with PET/CT may help plan treatment strategies and predict survival outcomes of these patients at diagnosis.

Purpose: To evaluate early changes in anterior segment parameters by Scheimpflug-Placido disc topography system and changes in retinal layers by optical coherence tomography in primary angle-closure suspects after laser peripheral iridotomyMethods: One eye of 26 patients with primary angle closure suspect and of 20 healthy subjects were included in this retrospective cross-sectional study. Anterior chamber depth/volume, iridocorneal angle and central corneal thickness were obtained by Scheimpflug-Placido disc topography system. Retinal thickness, retinal nerve fiber layer thickness and ganglion cell-inner plexiform layer thickness were acquired by optical coherence tomography. All the tests were repeated 1 week and 1 month after laser peripheral iridotomy.Results: The mean ages of the patients and healthy controls were 64.8±10.7 years and 64.5 ± 3.9 years, respectively (p=0.990). Anterior chamber depth/volume and iricorneal angle value were lower in the PACS group (p<0.001, for all). Anterior chamber volume and iridocorneal angle increased significantly after laser peripheral iridotomy (p=0.004, for both). While foveal thickness decreased significantly after laser peripheral iridotomy (p=0.027), retinal nerve fiber layer thickness increased in superior and temporal quadrants (p=0.038 and p=0.016, respectively).Conclusion: Our results suggest that LPI in patients with PACS provides improved retinal thickness and RNFL thickness, as well as anterior chamber parameters.