No abstract

Previous reports showed that tuberculosis is associated with increase free radical load and

Background: Highly active antiretroviral therapy (HAART) is widely used in the treatment of Human Immunodeficiency Virus (HIV) infection but toxicity is widely reported amongst patients. Hepatotoxicity is commonly reported among HIV patients on treatment with HAART, but there is lack of consensus between authors on whether liver disease seen in these patients is as a result of HAART or HIV infection itself. This study examined the possible effect of HAART on activity of liver enzymes, bilirubin level and Cluster Differentiation of Antigen (CD4+) in HIV patients on drug treatment. Methods: Forty (40) HIV patients on HAART (Group 1), forty (40) treatment naïve HIV patients (Group 2