Objectives: To identify clinical and laboratory characteristics of the Saudi children with confirmed COVID-19. Methods: Eighty-eight children)0-14 years(with COVID-19 who were admitted to Prince Sultan Military Medical City)PSMMC(, Riyadh, Saudi Arabia from April to June 2020 were recruited. Results: Mean age was 5.74 ± 4.7 years with 41)49.4%(males and 42)50.6%(females. The length of hospital stay)LOS(ranged from 1 to 17 days. The main source of infection was infected family members. Mean values of C-reactive protein)CRP(, serum ferritin, and lactate dehydrogenase)LDH(were noticeably above normal. Degree of severity and length of stay was significantly correlated with lymphopenia)r=-0.36; p=0.001(, Original Article whereas it was positively correlated with absolute neutrophil count and with high inflammatory markers, such as CRP, LDH, and others. Conclusions: Identifying the clinical and laboratory characteristics of the Saudi children with confirmed COVID-19 will improve understanding of this disease's presentation and will help put rapid and proper management strategies into place to face this pandemic. A high index of suspicion is needed for cases presenting with multi-system inflammatory disease, which represented 5.7% of the included study population.