Rol de las características clínicas e histológicas como factores pronósticos para la sobrevida en pacientes con carcinoma de células escamosas de la cavidad oral* Background: Survival of patients with oral squamous cell carcinoma is low and depends mostly on TNM staging of the tumor. Aim: To perform a retrospective analysis of a series of patients with oral squamous cell carcinoma. Material and Methods: Retrospective review of patients with the diagnosis, seen between 1995 and 2006 in a regional hospital. Host infl ammatory response and pattern of tumor invasion were assessed using the staging proposed by Bryne et al. Results: The medical records of 36 patients aged 39 to 89 years, were reviewed. During the study period, 15 patients died. Better survival was associated to a low pattern of tumor invasion and a high infl ammatory response and the topographic location of the tumor. Conclusions: Infl ammatory response, tumor invasion and location are associated with survival in oral squamous cell carcinoma.Key words: Oral cancer, squamous cell, survival. ResumenIntroducción: El carcinoma de células escamosas de la cavidad oral (CCECO) es una patología cuyo comportamiento es producto de interrelaciones con el huésped, esto es, por el patrón de invasión (PI) histopatológica y la respuesta infl amatoria (RI). El objetivo de este estudio es analizar las características clínicas e histopatológicas como factores pronóstico, en términos de supervivencia (SV) en pacientes con CCECO. Material y Método: Serie de casos. Se incluyeron pacientes diagnosticados en el Hospital Regional de Talca y Hospital Base de Curicó entre los años 1995 y 2006. Se revisaron las fi chas clínicas y biopsias de 36 pacientes con CCECO. Se determinó el Frente Invasivo Tumoral (FIT), evaluándose los parámetros propuestos por el sistema de graduación de Bryne (PI y RI) y factores de importancia clínica como localización topográfi ca de la lesión, edad y género, relacionándolos con SV mediante curvas de Kaplan-Meier y Log Rank test. Posteriormente, se aplicó una regresión de Cox para obtener un análisis multivariado y cálculo de RR. Del total de Rev.

Determination of the orbital volume has significance in cases such as facial injuries and lens implants where it is necessary to restore the normal position of the structures, since providing the patient with a volume-deficient orbit may result in enophthalmos. The aim of this study is to assess the volume of the orbit by using the Cavalieri's principle supplemented with sequential analysis of CT images on the computer screen. We conducted a series of CT images with a thickness of 1mm on 10 human skulls. After selection, initially random and then sequential, images were analyzed on a computer screen with a mesh test chart to determine orbital area. Once having identified both area and thickness, we measured the volume of segments, and the total volume of the orbit was extrapolated by using a mathematical formula based on the Cavalieri's principle. Results were compared with the actual volume obtained by the displacement of fluid from printouts of the orbits. The result of this comparison suggests that the method is statistically reliable when considering that we assessed seven images of a randomly chosen orbit and then in a known sequence with a straightforward technique for orbital volume estimation.