Background: Recovery time and fast patient discharge after surgery are goals of fast-track surgery that uses the concept of ERAS (Enhanced Recovery After Surgery) to minimize pain, speed up recovery, and reduce pain and complications. Fast-track surgeries such as odontectomy require drugs with a fast onset of action and short duration hence the patient can recover from the drugs as soon as possible. The use and types of opioids have been developed for optimal fast-track surgery. One of the most widely used opioids is remifentanil. Purpose: This study aims to compare the administration of fentanyl and remifentanil to the emergence and discharge time of post-odontectomy patients with general anesthesia. Methods: Patients were divided into two groups, the fentanyl group (group F, n=21) and the remifentanil group (group R, n=21). This study used a retrospective cohort analysis of the medical records of 42 patients with elective odontectomy surgery for the period December 2020 to June 2021 at RSUP dr. Hasan Sadikin Bandung. Emergence time was assessed using the OAA/S score and discharge time was considered using the modified Aldrete score. Results: This study showed a significant difference between the emergence time in group R (168+47.98 seconds) and group F (368+58.16 seconds) with a p-value = 0.0001. There was a significant difference between the discharge time in group R (20.00+7.24 minutes) and group F (58.57+12.46 minutes) with a p-value = 0.001. Conclusion: Recovery time and discharge time for patients receiving remifentanil were faster than for patients receiving fentanyl for odontectomy.