<p>The main objective of this research is studying phytochemical screening of the extracts of polluted <em>Nerium oleander</em> (L.), and unpolluted<em> Nerium oleander</em> (L.) collected from Meknes region (Morocco), and determination of metals concentration that can have harmful effects on human health. In addition, the study provides scientific data.</p><p>Studies have shown that the two extracts of polluted <em>Nerium oleander</em> (L.) and unpolluted <em>Nerium oleander</em> (L.) plant are rich in flavonoids, catechic and gallic tannins. In contrast, anthracene derivatives and flavonoids are absent. On the other hand, the comparative analysis of the results of atomic absorption spectrometry showed that the two plants of polluted <em>Nerium oleander</em> (L.) and unpolluted <em>Nerium oleander</em> (L.) contain a fairly high content of Na, Ca and Mg while the Pb concentration has exceeded the standard given by the WHO. While lithium and iron are present in low concentrations.</p>

The aim of this work is to determine the chemical composition of the essential oil of Origanum compactum, from the region of Meknes (Morocco), and their antimicrobial effect, and on the other hand, to carry out a comparison between the chemical composition of this essential oil with the six regions of Morocco: Larache, Chefchaouen, Al Hoceïma, Tetouan, Taounate and Rabat. The essential oils of Origanum compactum thus obtained were analyzed and identified by gas chromatography coupled with mass spectrometry (GC/MS). To determine the similarities and dissimilarities between the chemical compositions of the essential oil of Origanum compactum from the Meknes region with the other six regions of Morocco, we performed the principal component analysis (ACP). Regarding antimicrobial activity, the essential oils of Origanum compactum have shown significant inhibitory activity against the bacteria and molds studied.

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