Technology is improving day by day and every new face of it is engrossing, making applied science astonishment. Robotics and Artificial Intelligence have taken the world beyond automation. Automation was once considered as a challenge, but now the same technology has stunned the whole world, with the transformation of vision to the reality of live cell robots. In this modern era, evolutionary algorithms with Artificial Intelligence have made an impact on the automation and the creation of rare live-cell species by integrating biological aspects of frog cells. It would be thus useful in various domains to build technologies using self-renewing, and biocompatible materials of which the ideal candidates are living themselves. Thus, this paper presents a live cell robot named Xenobots, its design method, formation, applications, and transformation of live cell robots to humanoid robots that mimic the human brain.