Obesity and its concomitant health risks are among the most common conditions managed by health care practitioners. The limited long-term effectiveness of conventional weight management has led to researching alternative medicine and one which is widely accepted is the herbal products by virtue of its safety in long term use. The study was conducted to evaluate effect of caplet of Garcinia extract with reference to reduction in BMI and skin fold thickness in obese individuals. This study was performed according to a double-blind, randomized, placebo-controlled, design. Subjects aged 18 to 60 years with Obesity as decided by BMI > 25 Kg/m 2 to 35 Kg/m 2 falling in the category of overweight and class I obesity were included in the study. A total of 110 individuals participated in the study. Subjects were randomly assigned into two groups of 55 each to receive treatment for 4 months with Garcinia or matching placebo at a dose of 1 caplet twice daily. All the subjects completed the study as stipulated. At the end of 4 months, Garcinia group had significant reduction in BMI and skin fold thickness when compared to the placebo group and baseline values respectively. No severe adverse effect was observed at any time in the study period. Compliance to treatment was good. It is therefore expected that Garcinia may be useful for the prevention and reduction of obesity.

In Ayurveda, Atisar, has been defined as a condition where constant oozingout (Ati and sarana)of the liquid fecal matter from the anus. This condition is more or less similar to the sense of diarrhoea in western view. There are several anti-amoebic an antidiarrhoeal drugs are frequently used by the allopathic physicians for prevention and controlof the diseases. But those are having several adverse effects. From ancient era to till date Ayurveda has also contributed a lot of ‘Atisernasak’(antidiarrhoeal / antiameobic) herbs and compound medicine. ‘Mustak’(Cyperus rotundas, Linn) is one of the popular antidiarrhoeal remedy has been mentioned in different classical texts. In present study review of Ayurvedicliteratures have been done to collect the informations regarding the action of ‘Mustak’as well as pharmacodyanamics (Rasa, Guna, Virya, Vipak& Dosakarma). Methodical and scientific representation of those information have been furnished here with to justify the claim of Ayurveda that ‘Mustak’is a good remedy as ‘Atisarnasak’.After being reviewed of the literatures it has been found that ‘Mustak’ cures ‘Atisar’