Desiccant wheel dehumidifier is filled with solid desiccants, looks like a honeycomb structure which is open on both ends. Air is allowed to pass through the honeycomb passages, giving moisture to the solid desiccant contained in the wheel. The wheel constantly rotates through two separate air streams. The first air stream, called the process air is dried by the desiccant. The second air stream, called reactivation or regeneration air is heated and dries the desiccant. The combination of desiccant materials such as chloride desiccant and organic desiccant is used here and dehumidification in the composite desiccant wheel has been studied experimentally. In this work, study performance of composite desiccant wheel with different air velocities, regeneration temperatures and at different inlet conditions was conducted and calculated the different performance indices of the desiccant wheel dehumidifier such as Dehumidification Effectiveness and Dehumidification Coefficient of Performance (DCOP).