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This review is concerned with interrelationships between the functions of the central organs of the digestive system. Complex interdependences determine the final result, the integral behavior of the group of organs. Thus the mechanism of the self-regulation of the function of the organ follow the natural laws for a coordinated achievement of the objective by means of the mechanism of self-regulation of the function of the group of organs. Central influences ensure correlation of the behavior of the system as a whole.

It was established in chronic experiments on dogs that the introduction of neurotensin in a dose of 3 or 10 micrograms in 1.5 microliters into the caudate nucleus changes the parameters of the conditioned and unconditioned food reflexes: a 31% shortening of the latent period and a 56% increase in the magnitude of the reflex. Microapplication of neurotensin in the same doses in the posterior region of the hypothalamus enhanced the secretory function of the gland caused by the introduction of histamine. It was concluded that the caudate nucleus and hypothalamus contain cells possessing receptors for neurotensin, which participate in mechanisms of formation of the conditioned reflex and central influence on the organs of the digestive system.