The review presents data on the effect of program hemodialysis on the state of intraocular pressure in patients with terminal chronic renal failure. Treatment with hemodialysis is accompanied by various effects: from intraocular pressure drop to the development of ophthalmic hypertension with pain syndrome. The state of the iris-corneal angle, neovascularization of the structures of the eye drainage system and the presence of glaucoma are significant, but not indisputable, risk factors for pain-related dialysis ophthalmic hypertension. Their combination with the effect on the osmolar balance of dialysis therapy increases the possibility of the formation of ocular hypertension syndrome formation. The need to eliminate dialysis eye pains and the chance of glaucoma progression due to dialysis-affected fluctuations of intraocular pressure remains relevant.

The literature review discusses the impact of scheduled hemodialysis on the state of the anterior part of the eye, the chorioretinal complex, the central and peripheral vision. The hemodialysis procedure is accompanied by a decrease in basal tear production, quickening of the tear film break-up, and an abnormal ocular surface disease index. Thinning of the corneal center is not accompanied by significant keratometric changes. Intradialytic thinning of the choroid and reduction of ocular perfusion pressure may be involved in the progression of ischemic eye diseases. Lower visual acuity is associated with the instability of the lens and choroid thickness. The impact of hemodialysis on the peripheral vision has not been sufficiently investigated. The correlations of ophthalmic changes with systemic effects of the dialysis are ambiguous. The inconsistency of the research results requires that the research should be continued.

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PURPOSE. Comparative analysis of clinical and demographic characteristics of patients admitted for surgical treatment of primary open-angle glaucoma in the Krasnoyask Krai over the past 15 years.METHODS. The study analyzed 2426 medical histories of patients with primary open-angle glaucoma who underwent surgical antihypertensive intervention at the Krasnoyarsk Regional Ophthalmic Clinical Hospital named after Professor P.G. Makarov in 2007–2021.RESULTS. It was found that the proportion of men was significantly higher than women among patients who underwent surgical treatment of glaucoma. The mean age of operated patients was comparable across the entire period and ranged from 66.4 to 69.0 years. The proportion of patients with advanced stage of the disease increased during the study period from 50.7% to 75.5% (p<0.001). In 73–83% of cases, interventions were performed on patients with uncompensated, moderately elevated or high intraocular pressure.CONCLUSION. Considering the dominating proportion of eyes with advanced stage of the disease (50.7–75.5% of cases), as well as high initial levels of intraocular pressure, it can be assumed that in some cases such patients are still referred to surgical treatment late, although presently it can be associated with problems in planned care due to the ongoing pandemic.