No abstract

A rapid FTIR spectroscopic method has been proposed for the estimation of Gliclazide in bulk drug and pharmaceutical dosage form. The method involves the measurement of the area of the infrared band corresponding to the amide stretching centered at 3317cm -1 . The excipients in the commercial tablet preparation did not interfere with the assay. The linearity range was found to be 4-24µg/ml. The technique is reliable and useful for quality control for monitoring the adulteration of pure drug. The proposed method is statistically validated and found to be useful for the routine determination of gliclazide in tablets.