Pregnancy represents a physiological status which, due to clear and typical hormonal and hemodynamic changes, is frequently accompanied by a high morbidity of aortic structures, in all of its segments. Such morbidity might become patent when a pregestational situation exists, especially with the mother suffering from connective tissue disorders. Nevertheless, morbid occurrences that will be met only during pregnancy are well known, with particular pathophysiological and etiological theories, as well as a diversity of treatments proposed in such an unusual setting. The authors discuss the main pathologies of aorta that are seen during pregnancy, from a theoretical point of view, and from a historical perspective as well. A special focus is made to the connective tissue disorders, and the theoretical considerations are illustrated with images of dissecting aneurysms of aorta.

Introducción: El glioblastoma multiforme (GBM) es el más frecuente y maligno de los tumores cerebrales. Su presentación en cerebelo es excepcional. Caso clínico: Paciente de 42 años con historia breve de trastorno de la marcha y cefalea. La resonancia magnética cerebral mostró una lesión de unos 4 cm de diámetro sólida y quística, con edema, en hemisferio cerebeloso dcho. Se extirpó un Glioblastoma multiforme con p53 positiva. Conclusiones: La edad y la p53 hacen pensar que se trate de una forma secundaria de GBM. La bibliografía revisada constata que se trata de una localización infrecuente. El tratamiento inicial es quirúrgico pero las supervivencias son cortas a pesar de la radioterapia y del uso de nuevos quimioterápicos como la Temozolomida. Palabras clave: Glioblastoma. Proteína p53. Tumor Fosa posterior. Tumor de cerebelo.