HydroalcoholicextractofGreeneriesandstalkbarkofFicusgibbosaBlume is evaluated for their potentiating action in Streptozotocin – Nicotinamide encouraged type 2 diabetes in Sprague Dawley rats. The excerpts are managed at the amount of 100, 250 and 500 mg/kg body weight along with sub operative dose (2.5 mg/kg body weight) of the standard antidiabetic drug (Glibenclamide) for a period of 5 weeks. The test extracts potentiated the antidiabetic activity of standard drug by significantly dropping the raised blood glucose levels and the effect was almost comparable with solitary efficacy of therapeutic dose (5 mg/kg body weight) of typical drug Glibenclamide during 5th week of the study. Its abandons have deviated, on the other hand, orchestrated and more gibbose in those end. The juice of the bark furthermore abandons from claiming color fig alternately bumped fig plant is utilized to grinding those pills furthermore settling on A decoction in toxicology. Plant appeases diminished Kapha, pitta, skin diseases, ulcers, hepatopathy, diabetes, ulcerative stomatitis, leucorrhoea and gynaecological issues. Male Sprague Dawley Rats abstainedinstantare vaccinated intraperitoneally with result about Nicotinamide at a dosage of 195 mg /kg body weight. 15 minutes after same animals are vaccinated for the newly readied result from claiming Streptozotocin (STZ) In measurement about (65 mg/kg physique weight) intraperitoneally. The animals are permitted to drink 1% glucose result instant will succeed the pill prompted hypoglycaemia.
The main aim of the study is to assess and evaluate the drug related problems in the pulmonology department. It was a Prospective Interventional study in PULMONOLOGY DEPARTMENT conducted at Manipal Super Speciality Hospitals, Vijayawada, Andhra Pradesh for a period of twelve (12) Months from February 2018 to February 2019. We have collected 115 cases from Pulmonology Department. During the study period, we have collected a total number of 115 cases under the pulmonology department. We found that Males are more effected than Females with percentage of 68% (n=78) and 32% (n=37). In the present study 27 DRP’s were found in which 10 Adverse Drug Reactions, 4 Untreated conditions, 4 Inappropriate drug according to guidelines, 4 inappropriate timing of administration, 2 Drug dose too high, 2 No Drug treatment inspite of existing indication, 1 prescribed drug not available. The result of the present Interventional study shows that Clinical pharmacy services helps in identify and resolve drug related harms in discussion with health care professional. In our study we found 27 DRP’s based on PCNE V8.02 classification in which 22 DRP’s were informed to the physician, and 5 DRP’s were identified by the physician. The study shows that there is a need for Clinical Pharmacist services in healthcare to reduce DRP’s by monitoring patient’s drug therapy by which Pharm. D (Doctor of Pharmacy) can be suggested as Clinical Pharmacist since they are well versed in the subject areas like Clinical pharmacy, Clinical Pharmacology, Clinical Toxicology and Pharmacotherapeutics.
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