1,3-Dipolar cycloaddition of in situ generated non-stabilized azomethine ylides through the decarboxylative condensation of sarcosine and substituted isatins with 2-(arylmethylene)-2,3-dihydro-1H-inden-1-ones in microwave produced dispiro[1H-indene-2,3Œ-pyrrolidine-2Œ,3ŒŒ-[3H]indole]-1,2ŒŒ(1ŒŒH)diones in a highly stereo- and regio-selective fashion. The synthesized compounds were subjected to antibacterial and antifungal studies. It was found that many compounds possess a considerable antibacterial and antifungal activity against all the tested organisms.

A series of metal complexes have been synthesized by the reaction of Schiff base with metal (II) salt solution. The complexes were characterized by UV and FT- IR studies. The study reveals that the geometry of the complexes were octahedral. The electronic spectra of these complexes show a strong absorption band in 550 - 580nm region. This confirms the coordination of ligand with metal. The FT-IR shows a very strong band at 1616cm-1assigned to C=N stretching vibration. It is shifted to lower wave number because of the complex formation, suggesting that coordination of the Schiff base groups through N- atoms with the metal ion. The band at 3496 cm-1is due to aromatic N-H stretching, It is noted that a broad band of the asymmetric and symmetric O-H stretching mode around the region 3400 cm-1presumably due to H-O-H bending vibrations are not observed in the spectrum of complexes, which are indicating of the absence of the water molecule.

A series of metal complexes have been synthesized by the reaction of Schiff base with metal (II) salt solution. The complexes were characterized by UV and FT- IR studies. The study reveals that the geometry of the complexes were octahedral. The electronic spectra of these complexes show a strong absorption band in 550 – 580 nm region. This confirms the coordination of ligand with metal. The FT-IR shows a very strong band at 1606cm-1 assigned to C=N stretching vibration. It is shifted to lower wave number because of the complex formation, suggesting that coordination of the Schiff base groups through N- atoms with the metal ion. The band at 3056cm-1 is due to aromatic O-H stretching, the sharp peak at 750 cm-1 and 688 cm-1 are due to halogens substituted in the para position.