Herein we report an alternative eco-friendly method for the synthesis of
1,2,3,4-tetrahydroisoquinoline sulfonamide derivatives. All obtained
compounds were screened for their in vitro inhibition of albumin
denaturation, antioxidant, antitryptic, and antibacterial activity and have
shown significant results. The lipophilicity was established using both
reversed-phase thin layer chromatography and in silico calculations.
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