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ДУ «Інститут дерматології та венерології НАмН України», м. Харків 2 Українська військово-медична академія, м. Київ Наведено клінічний випадок-чоловік, 41 рік, з проявами хронічного уретропростатиту, спричиненого Chlamydia trachomatis та, вірогідно, Trichomonas tenax. Послідовне проведення двох курсів лікування, що були спрямовані на елімвінацію збудників поєднаннями орнідазолу та ніфурателю, а також джозаміцину та геміфлоксацину, дозволило досягти етіологічного та клінічного одужання.

дерматологии и венерологии НАМН Украины» 2 Украинская военно-медицинская академия Министерства обороны Украины 3 Научно-инженерный центр профессиональной лабораторной диагностики «Днепролаб» Резюме Цельгенотипирование T. vaginalis, обнаруживаемых у больных урогенитальной патологией в Украине. Материалы и методы. Проведено генотипирование T. vaginalis методом Crucitti T. et al. в 29 образцах, полученных у больных c с хронической урогенитальной патологией в северо-восточном и центральном регионах Украины. Результаты. Наиболее распространенным выявился генотип Е (68,9%), реже встречались генотипы G (20,7%), H (10,35%) и A (3,45%). Выводы. Наиболее распространенным генотипом T. vaginalis, циркулирующих в Украине, является генотип Е, значительно реже встречаются возбудители генотипов G, H и А. Не выявлено взаимосвязи генотипа с клиническими признаками заболевания.

Study of protozoyny invazions of the uroganital system with combination of microorganisms which are associated with bacterial vaginosis by women of fertil age and their sexual partners men is perspective direction of modern medicine. The development of this direction can increase the level of diagnostic inspection of patients by transmissible mainly sexual way infections and improve of efficiency of their treatment. The objective: exposure of combine defeats of uroganital system with different kinds of trichomonas or lamblias and microorganisms which are associated with bacterial vaginosis, for the women of fertil age and their sexual partners – men. All patients have infections, transmissible mainly sexual way with a chronic process and their treatment. Materials and methods. The special research of biomaterial, taken from the urogenital system of women of fertil age and their sexual partners-men, patients infections, transmissible mainly sexual way with a chronic process is conducted. 198 patients were inspected in clinic. Used the method of PCR, amplifier of DT-96, reagents of «Femoflor-16», praymeris for the indication of Trichomonas vaginalis, Trichomonas tenax, Pentatrichomonas hominis and Giardia lamblia. Results. Protozoyny invasions of the urogenital system determined at 88 (44.4%) of patients. At 77 (38.8%) from them determined the differet kinds of trichomonadies: Trichomonas tenax – at 41 (20.7%), Pentatrichomonas hominis – at 28 (14.1%), Trichomonas vaginalis – at 8 (4%). Giardia lamblia determined from 11 patients (5.6%). For 92% inspected patients with a protozoal invasions were determined the increassng of indexes of microflora, associated with bacterial vaginosis. The treatment of combine pathology of urogenital system which are caused different kinds trichomonades and microorganisms, which associated with BV, were conducted with etiotropic therapy. Seknidox used 2 tablets one time per day during 5 days. Orcipol used 1 tablets 3 or 2 times per a day (depending on weight) during 10 days. In research took part 56 patients with chronic ITSW. By 54 patients (96.4%) were eliminated of trichomonas. The normalization microflora’s level is attained for a 31 (57.4%) patient. Decrease of mocroflora’s, which associated with BV is marked by 24 patients (42.6%). Conclusions. This original method of treatment, is effective, has satisfactory bearableness and can be recommended for empiric therapy of combined pathology of urogenital system, caused of protozoyny invasions (different kinds of trichomonas) and microorganisms, associated with bacterial vaginosis, for the women of fertil age and their sexual partners with chronic infections, transmissible mainly sexual a way. This agents have a certain role in development of diseases of the urogenital system. Key words: Trichomonas vaginalis, Trichomonas tenax, Pentatrichomonas hominis, Giardia lamblia, invasion, fertil age.

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