The article presents a clinical case of urgent surgical treatment, laparoscopic removal of the spleen in a comorbid patient in serious condition. Surgical treatment was carried out according to vital indications, a smooth postoperative period. With dynamic observation, a possible consequence of surgery is the occlusion of large vessels of the brachiocephalic tree. A multidisciplinary approach, which also extends to the conditions for providing medical care to a patient in the "red zone", clinical attentiveness and integration of services made it possible to save the life and achieve good rehabilitation for the patient despite the comorbid aggravation of her condition.