LI13109F is a novel herbal composition containing the extracts of Boswellia serrata gum resin and is tolerable and an effective intervention for management of mild to moderate asthma such as airway inflammation.

Adenosine deaminase activity was estimated in 75 patients of pleural effusions of different etiologies. Patients were classified into three groups Tuberculosis (55), malignant (10) transudates (7), purulent effusion (3), based on diagnosis made on fluid examination and other investigations. The diagnosis was made independent of ADA activity. Out of 55 cases of tuberculous pleural effusions 54 have ADA activity of >40IU/1 Mean ADA activity in Tuberculous pleural effusions is significantly higher (66.41±29.31) than that of malignant pleural effusions (p<0.001). Mean ADA activity in malignant pleural effusions (17.32±2.641) is significantly higher than that of Transudative pleural effusions (11±3.12) (p< 0.001). ADA activity has no relation to the radiological extent of effusion and sputum status for AFB. There is no significant difference in ADA activity between males and females. All malignant pleural effusions have mean ADA levels less than 40 IU/1. The sensitivity, specificity and positive predictive values obtained for tuberculous pleural effusions in the present study are 98.8%, 100%., 100% respectively (taking 40 IU/1 as a cut off limit to discern tuberculous from non-tuberculous effusions). The results of the present study confirm that the ADA activity in pleural fluid is a very good parameter for the differential diagnosis of pleural effusions, compared to the conventional tests. ADA estimation is simple, low cost and least invasive and should be considered in the routine study of pleural effusions, particularly if diagnosis of tuberculosis is contemplated and in places where prevalence of this disease is still high.

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The study entitled "A Study on Performance of DOTS in a Private Medical College Hospital" was conducted in the area of ELURU town which is served by DMC of ASRAM Medical College to assess the performance of RNTCP at a premier tertiary level hospital of the state of Andhra Pradesh. This was both a hospital and community based prospective and follow-up study. Different technical indicators were considered to analyze the findings. Reference for sputum examination from ASRAM OPD (which include pulmonary medicine OPD) is 2.34% which is according to RNTCP norm>2%. Among the total new OPD registrations, 2.31% were chest symptomatic in the year 2011 and had undergone sputum smear examination for AFB. Among them 13.31% were detected to be sputum positive.91 of 122 cases that were diagnosed at ASRAM Medical College to be new smear positive were either referred to or transferred out to other DMC or TU respectively for DOTS. Ratio of patients among different categories in present study is found to be Cat-I: Cat-II is: 4.27:1 Retreatment case load of this DMC was 19% (RNTCP norm: ≤ 30%). A total of 58 patients had been registered in 2011 for DOTS under DMC of ASRAM Medical College. Among them 43 (74.13%) were males and 15 (25.86%) were females. Most of them (51.72%) belong to socioeconomically productive age group of 15-44 years. 65% of study subjects are illiterate or have low level of literacy which has a significant role in the spread and prevention of the disease in the community.68.97% of cases belong to low socioeconomic class which indicates that this disease still exists as a disease of poor men.

A Cross Sectional study was carried out on 100 patients with pleural effusion from December 2013 to July 2015 at ASRAM Medical College and Hospital Department of Pulmonary Medicine,Eluru. In our study, Exudative effusion remains most common cause of pleural effusion.Tubercular effusion remains the commonest etiology of all exudative effusions, where as Congestive cardiac failure remains commonest cause among transudative effusions.Tubercular effusion affects most commonly young and is associated with cough and fever as the most common presenting symptom. Malignant effusions were seen in older age group with cough and dyspnoea as predominant symptoms.Massive effusion with hemorrhagic pleural fluid is commonly associated with malignant effusion while small to moderate effusions with straw colour pleural fluid is associated ubercular effusion where as empyema cases presented with pus. Right sided effusion was most common with male to female ratio of 3.54:1 ,with mean age of 40.5+11.3 years.Empyema was most commonly associated with high Leukocytes.Tubercular effusion was associated with lymphocytic predominant effusion where as neutophilic dominant effusion included empyema and parapneumonic effusion.Pleural fluid, with low glucose (<40 mg/dl) was seen predominantly in empyemas. Pleural LDH to serum LDH ratio >2 was seen predominantly in empyemas .A pleural fluid ADA more than 70 IU/L was associated with nearly half of Tubercular effusions , where as others with ADA levels between 30 to 70 IU/L along with clinicoradiological findings suggestive of tubercular effusion. Thus proving diagnostic importance of ADA in TB effusions.Early intiation Anitubercular drugs in TB pleural effusion, early intervention and treatment in cases of empyema and parapneumonic effusion showed improvement and signs of recovery.