P. Zhang scite author profile

Background:The cornerstone of the management of Beta Thalassemia Major (B-TM) is lifelong Red Blood Cells (RBC) transfusion. This is associated with the development of RBCs alloantibodies. Human Leukocyte Antigen (HLA) is considered a risk factor for a number of autoimmune disorders. We hypothesized that HLA impacts the rate of alloantibody formation in patients with B-TM. Aims: To assess the impact of HLA alleles on the risk of RBC alloimmunization in patients with B-TM.

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P. Zhang

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