Transcatheter aortic valve implantation (TAVI) is an alternative treatment for severe aortic valve stenosis (AS) in patients with prohibitive risk for surgical aortic valve replacement (SAVR). Prosthetic valve endocarditis (PVE) is a rare complication of this relatively novel procedure and current guidelines do not include specific recommendations for its treatment. We report a case of PVE due to Pseudomonas aeruginosa after TAVI that required SAVR, with successful outcome. PVE usually occurs during the first year after TAVI and entails a high mortality risk because patients eligible for this min-imally invasive procedure are fragile (i.e. advanced age and/or severe comorbidities). Additionally, clinical presentation may be atypical or subtle and transesophageal echocardiogram (TEE) may not be conclusive, which delays diagnosis and treatment worsening the prognosis. This case highlights that open SAVR might be ultimately indicated as part of treatment for TAVI-PVE despite a high-risk surgery score.

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La presencia de trombos en cavidades izquierdas no suele ser algo que se observe con mucha frecuencia. Su presencia, en general, es secundaria a una agresión sobre el músculo cardíaco, como un infarto agudo de miocardio. Habitualmente, el manejo es conservador (mediante tratamiento anticoagulante), pero en el caso de trombos muy extensos o eventos embólicos se prefiere la vía quirúrgica.