Netarsudil (Rho-associated protein kinase inhibitor) is one of the newer anti-glaucoma medications used for the management of glaucoma. It has the most common side effects, such as conjunctival hyperemia, subconjunctival hemorrhage, and cornea verticillata. This manuscript focuses on a rarer side effect of netarsudil-associated reticular corneal epithelial edema, after netarsudil application for 3 months in a 62-year-old male. This side effect is rarely reported in the literature. In this manuscript, netarsudil-associated reversible corneal epithelial edema and its management have been reported.
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