Oral lichen planus (OLP) is a T cell-mediated chronic autoimmune disorder directed against antigens secreted by the basal cell layer, with an incidence of 0.02-0.22% in Indian population and showing female predilection. Stress is considered one of the etiological factors in the causation, progression, and recurrence of this disease. To evaluate the levels of serum cortisol, anxiety, and depression in patients with symptomatic OLP and to correlate the levels of serum cortisol with anxiety and depression. Sixty subjects were categorized into two groups. Group A: 30 adults with no history of OLP and no psychological history of anxiety and depression. Group B: 30 patients with clinically and histopathologically diagnosed symptomatic OLP. The subjects in both groups were evaluated for anxiety and depression levels using the Hospital Anxiety and Depression Scale (HADS) questionnaire and serum cortisol levels (8-9 am sample) using the chemiluminiscence method. Higher Serological and psychological assessment of patients with OLP

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Background: Temporomandibular disorders (TMDs) constitute clinical problems that involve the masticatory muscles, the temporomandibular joints, associated structures, or both. The etiology of TMDs is multifactorial. The association between occlusal interferences and TMD is controversial.. Objectives: This study is designed to evaluate the clinical outcome of T-Scan guided occlusal equilibration in patients suffering from TMD associated with occlusal discrepancies. Materials and Methods: A total of 15 patients clinically diagnosed with TMD based on the Diagnostic Criteria for Temporomandibular Disorders and with positive occlusal interferences were included in the study. The occlusal equilibration was achieved by performing T-Scan guided Immediate Complete Anterior Guidance Development. Results: The obtained data was subjected to statistical analysis using SPSS version 20.0 software. There was a statistically significant reduction in the occlusion time, i.e., from 0.77 ± 0.6 pre-treatment to 0.31 ± 0.2 post-treatment (P = 0.005), and also disclusion time, i.e., from 1.71 ± 1.09 pre-treatment to 0.11 ± 0.03 post-treatment (P = 0.000). There was a statistically significant reduction in the VAS score post-treatment (P = 0.000). Conclusion: T-Scan guided occlusal equilibration in TMD patients has resulted in significant improvement of symptoms. Hence, we emphasize the importance of the identification and correction of occlusal interferences in the management of symptomatic TMDs.