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The COVID-19 pandemic is a major public health issue that has affected millions of people in many different manners. This research proposes a novel approach to study and monitor this pandemic's impact on Twitter users concerning Social Isolation. Various sets of analyses is conducted to identify potential correlations between tweets related to social isolation, people's movement trends, and their emotional status. In this research, multiple datasets are used, ranging from our own collected dataset to a huge COVID-19 twitter dataset with over 140 million tweets and from the Google mobility report to the World Health Organization dataset. A couple of cloud-based services are used to analyze this data and extract patterns and insights from them. We believe the results of this research can be used as a public health indicator to anticipate the possibility of social isolation and design the health policies accordingly.

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