Abstract. Most scientific communities have recently established policies and mechanisms to put into practice electronic conference management, mainly by exploiting the Internet as the communication and cooperation infrastructure. Their foremost objective is to reduce the operational and communication costs but to maintain high quality reviewing and the fairness of the evaluation process. Interestingly, we report on experience gained by an implemented system named Confious. Confious [8] is a state-of-the-art management system that combines modern design, sophisticated algorithms and a powerful engine to help the program committee (PC) Chair to effortlessly accomplish a number of complicated tasks and carry out the necessary activities to produce the proceedings of a scientific conference. We are principally interested in (a) describing the workflow dynamics of a real-world scientific process, (b) identifying the main concerns of the person in charge of the conference organization, (c) providing mechanisms that enable the efficient management and monitoring of the overall coordination process.
Background. Gynecologic melanomas are extremely rare malignancies, and primary malignant melanoma of the cervix (PMMC) is the rarest among them all, with less than 100 cases reported so far. Although some conditions have been correlated with the pathogenesis of this entity, no specific risk factor has been yet identified, with vaginal bleeding being the most common symptoms. The diagnosis is based on physical examination with speculum assessment and cytologic and histopathologic findings accompanied with immunohistochemical staining of lesion’s biopsies. Case Presentation. We report a case of PMMC in a 34-year-old para-2 patient, among the youngest cases of PMMC reported, that presented to our clinic for routine examination. Gynecologic examination demonstrated a dark, heavily fully pigmented cervical growth completely covering the entire external cervical os. Biopsy obtained and showed malignant melanoma. She underwent radical hysterectomy with bilateral salpingo-oophorectomy and pelvic lymphadenectomy. The pathological diagnosis was FIGO stage IB1 PMMC. Despite 2 courses of anti-PD-1 antibody (Nivolumab) treatment, the patient passed away 13 months after diagnosis (12 months after surgery). Conclusions. Early diagnosis and subsequently early treatment are of high importance regarding patients’ prognosis and survival. No standardized protocols or treatment guidelines specific for this rare cancer have been issued; thus, clinicians are called to assess each case individually. Current treatment options are based on surgical excision mostly with radical hysterectomy, but in advanced or recurrent state of the disease, other treatment modalities, such as chemotherapy, radiotherapy, and immunotherapy, can be employed. Prognosis for these patients is very poor, and survival rate remains extremely low, with the median OS reported being less than 2 years. Reporting and publishing of such cases are both of paramount importance for the better understanding of this uncommon cervical malignancy, and further biological and clinical investigations are required for more suitable and effective therapies to be determined. A new staging system, specific to PMMC, could be of great use for the better correlation of the disease’s stage and prognosis of these patients.
Purpose The study aims to investigate backlogs within the picking procedures, to find out what is causing storage picking bottlenecks, and to estimate its effect on creating throughout warehouse picking operations. Design/methodology/approach For this study, a survey questionnaire was used to collect data from a primary source. The staff of the Gulf Nails Enterprise was taken into account as the population of the study. A total of 20 responses were recorded from the population of 50 persons employed in the company. The collected data was analyzed quantitatively to bring out the results. Findings The findings confirmed that most of the warehouse pickup area bottlenecks occur due to the least adaptation towards technologies. It is shown that the bottleneck issue could affect 20 to 30 percent of the production line. It is also evidenced that not only tools but strategic planning and efforts by the staff are extremely important in solving a bottleneck issue. Research limitations/implications The study recommended that an inventory management system would keep the bottlenecks in check. Introducing modern technology could help to solve such issues so that human efforts would not be wasted. It is also suggested that the firm should not rely fully on technology solutions as it is also one of the causes of bottlenecks. Social implications This paper will help understand, recognize and solve the various issues faced by the majority of companies in the area of warehouse pickups, not only in Oman but outside as well. Originality/Value There has been a lot of studies and research on several areas of warehouse operations but none so far on the topic of the general pickup area of the warehouse.
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