Material-binding peptides (MBPs) are functionalized adhesive
materials
consisting of a few to several dozen amino acids. This affinity between
MBPs and materials is regulated by multiple interactions, including
hydrogen bonding, electrostatic, hydrophobic interactions, and π–π
stacking. They show selective binding and high affinity to a diverse
range of inorganic and organic materials, such as silicon-based materials,
metals, metal compounds, carbon materials, and polymers. They are
used to improve the biocompatibility of materials, increase the efficiency
of material synthesis, and guide the controlled synthesis of nanomaterials.
In addition, these can be used for precise targeting of proteins by
conjugating to target biomolecules. In this review, we summarize the
main designs and applications of MBPs in recent years. The discussions
focus on more efficient and functional peptides, including evolution
and overall design of MBPs. We have also highlighted the recent applications
of MBPs, such as functionalization of material surfaces, synthesis
of nanomaterials, drug delivery, cancer therapy, and plastic degradation.
Besides, we also discussed the development trend of MBPs. This interpretation
will accelerate future investigations to bottleneck the drawbacks
of available MBPs, promoting their commercial applications.
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