Nutrisound Dry Concentrate (NDC), a mycotoxin control product based on a specialized cell-wall deficient bacterium, was recently introduced in Thailand, a region typically experiencing multiple mycotoxins in production animal agriculture. Field evaluations of this product were conducted on a commercial swine farm. In experiment 1, approximately 1000 weaned pigs (large White x Landrace x Duroc, 28 days of age) were randomly allocated to two groups, control (CON) and treatment (NDC). Each group was housed in 14 pens of 35–36 piglets/pen. A common basal diet (rice/soy) was prepared that included an anti-mycotoxin product. This was the CON feed; and that same diet, to which NDC was added (1.2 kg/tonne), was the treatment ration. In the 42 day trial, NDC improved body weight, gain, and feed intake (P < 0.05) and reduced mortality by half (P < 0.05). Fecal coliforms and E. coli were reduced significantly (P < 0.01). A second study was conducted with 50 sows per group, each group fed diets identical to those of the piglet experiment. The experimental diets were fed for the last 5 weeks of gestation (typically, NDC is fed for at least 9 weeks of gestation). While not significant, there was a trend in the NDC sows for improved farrowing rate and piglet birth weight (P < 0.10) Thus, NDC yielded performance improvements in both young pigs and gestating sows. However, repeated tests for 16 mycotoxins/metabolites revealed no major dietary mycotoxins. NDC/s active principle is a cell-wall deficient bacterium. These are highly interactive with mucosal immune functions. Additionally, NDC has a low inclusion level (106 cfu/gm) of B. subtilis. In the absence of confirmed mycotoxins, immunological support could be the source of improved performance. It is also possible that mycotoxins not routinely assayed were present. In that case, NDC provided the expected broad spectrum protection against undetected mycotoxins.