Objective: To assess the postoperative outcomes of laparoscopic appendectomy in terms of  compli- cations and to compare them on gender basis. Methods: This was the prospective observational study conducted at department of General Surgery Chandka Medical College Hospital Larkana with non-probability convenient sampling technique. The duration of study was one year  from  January  2013  till  December  2013.  150  patients  were  selected  that were diagnosed with acute appendicitis. Patients were followed up for 2 weeks and their compli-  cations were observed. All data was entered  and  analysed  on  SPSS  version  20.  Inferential  analysis was performed using chi-square test whereas the significance level was set at 0.05. Results: The study results showed that 14 male (18.7%) and 16 female (21.4%) patients developed complications (p=0.094). 5 male (6.6%) and 8 female (10.6%) patients  developed  paralytic  ileus  (p=0.384). 5 male  (6.6%)  and  3  female  (4%)  patients  developed  urinary  retention  (p=0.471)  whereas 2 male (2.6%) and 6 female (8%) patients complained to have wound infection (p=0.146). The overall frequency of patients that did not develop any  complications  among  150  patients  was  121  (80.6%)  while 13 (8.6%), 8 (5.3%) and 8 (5.3%) were reported to develop paralytic ileus, urinary retention and wound infection respectively. Conclusion: Laproscopic appendectomy is safer and  clinically  advantageous  technique.  The  differ-  ence in the complications of the laproscopic appendectomy with  respect  to  the  gender  was  insignifi- cant. However, significant difference existed on visual analogue pain scale.