Background: CD44 isoforms are known to be possible diagnostic and prognostic markers in colorectal cancer (CRC). Objectives: The present study aims at investigating the expression of CD44 standard (CD44s) isoform in CRC by immunohistochemistry (IHC) as well as exploring its clinicopathological correlations. Methods: A total of 102 patients, who underwent surgery for primary colorectal adenocarcinoma, were enrolled in this study. IHC staining for CD44 was performed on pathology samples and defined as: staining < 10% as low/weak, 10% -50% as moderate, and > 50% as strong/extensive expression level.

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