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In cancer patients, syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the leading cause of hyponatremia. 1 Hyponatremia is a serious disorder of dyselectrolytemia, linked with neurological symptoms that are life-threatening and it is the most common aetiology of tumour-related electrolyte imbalance.2 The tumours commonly causing hyponatremia of SIADH variety are lung, head-neck and breast tumours. SIADH has been documented in various malignancy types with numerous possible aetiologies apart from active malignancy.2,3 The aetiology distribution of SIADH in tumour patients are not completely known. Secondly, clinically, it is not clear which malignancy is most commonly associated with SIADH.3 Calcified meningioma presenting as SIADH had not been reported so far in the literature. Here a case of an elderly female with clinical features and brain imaging suggestive of meningioma associated with hyponatremia due to SIADH had been highlighted.

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Snake bite is predominantly an occupational hazard and causes severe health issues. Snake poisoning in India is a significant and prevalent cause of Acute Kidney Injury (AKI). In India, the occurrence of AKI after snake bite is 13-32%. All over the world every year, 1,50,000 people die as a result of it. Multiple mechanisms such as haemodynamic disturbances, direct tubular toxicity, coagulopathy, haemoglobinuria, and myoglobinuria can cause AKI after bites by snakes belonging to the Elapidae, Viperidae, and Colubridae families. Renal pathologic findings include acute tubular necrosis, cortical necrosis, interstitial nephritis, glomerulonephritis, and vasculitis. Thrombotic Microangiopathy (TMA) as a cause of snakebite-induced AKI is rarely reported in literature. Fewer details are known about the clinical course, optimal management, and overall prognosis of this entity. Haemolytic Uremic Syndrome (HUS) is a clinical disease that includes TMA, thrombocytopenia, and AKI as a triad. The HUS is a heterogeneity of illnesses with diverse aetiology which results in presentation, therapy and outcomes variance. Hereby, authors report a case of a 55-year-old female who was bitten by Russell’s viper and developed HUS. Patient eventually progressed to end stage renal disease and was advised lifelong haemodialysis. TMA should be taken into account as a probable cause of AKI following a snake bite. Plasma exchanges have yet to be determined in snake bite TMA.