The purpose of this study was to investigate the perceptions of high school principals about the organizational health of the district and its relationship with their job motivation. To achieve this goal, correlation method and multiple regression analysis as research method was adopted.by using cluster random sampling method, a sample of 271 principals was chosen from the population of high school boys and girls in the education districts of Tehran, Iran and their perceptions about Organizational Health and Job Motivation was assessed by two questionnaires. Data collection tools were the Hoy and Feldman Organizational Health Inventory (OHI) and the Hackman and Oldham Job Characteristics Questionnaire(JCQ). These instruments had favourable psychometric indices (validity and reliability). The findings indicated that there is a positive and significant relationship between organizational health and job motivation of principals, and there is also a significant positive relationship between the components of organizational health and the dimensions of job motivation. Data analysis using multiple regression analysis revealed that 29% of changes in principals' job motivation are determined by organizational health (a component of institutional integrity). These data show that secondary school principals' perception of organizational health has an important and significant role in their job motivation and their desire to perform professional functions, and among the elements of organizational health, institutional integrity has the greatest impact on managers' motivation towards It has its own profession.