In addition to HBV/D and HBV/A, a significant proportion of HBV/C (23.4%) was also present among the voluntary blood donors from eastern India, most frequently in the 18-25 year age group. BCP mutation was more common in HBV/C infected donors.

Ataxia-telengiectasia (AT) is characterized by slowly progressive cerebellar ataxia, occulomotor apraxia, choreoathetosis, telangiectasis of the skin and conjunctivae, susceptibility to sinobronchopulmonary infections, lymphoreticular neoplasia, other malignancies, and sensitivity to ionizing radiation. It was described by Syllaba and Henner in 1926, by Louis-Bar in 1941, and more definitively in 1958 by Boder and Sedgwick, who presented the first clinical and neuropathologic delineation of the disease and named it AT. [1]

No abstract

Marinesco-Sj?gren syndrome is a rare syndromic disorder with distinctive features of cerebellar atrophy, developmental delay, congenital cataract and other associated features. It is an autosomal recessive disorder. Only 100-200 cases have been diagnosed worldwide until now. Only two previous reports could be found from India-one describing two cases and another report of three affected siblings. Here we describe a family with two affected siblings from Kolkata, India.

Banded spherulitic growth of crystal is observed in some materials with spherically symmetric growth front and periodic radial variation of birefringence. This variation of birefringence in quasi two dimensional geometry produces concentric interference colour bands when viewed through crossed polarisers. In most materials, the banded spherulites are found to be formed by radially oriented periodically twisted fibrillar crystallites. Here, we report the formation of banded spherulites due to the rhythmic growth of concentric crystallite-rich and crystallite-poor bands for a pure compound consisting of strongly polar rod like molecules. The compound exhibits coexistence of untwisted fibrillar crystallites and an amorphous phase in its most stable solid state. On sufficient supercooling of the sample from its melting point, the banded spherulites are formed with a periodic variation of composition of untwisted radially aligned fibrillar crystallites and an amorphous solid phase. We have developed a time dependent Ginzburg-Landau model to account for the observed banded spherulitic growth.