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The Guide to the Expression of Uncertainty in Measurement GUM is not systematically used in medical laboratories, for what the laboratorian should understand the Uncertainty "pproach and its importance to recognize the level of realism of results. This chapter presents, discusses, and recommends the models fulfilling GUM principles. "n example is given to a single test for an easier understanding of the determination of measurement uncertainty. "ll the practice uses a freeware. Results with larger measurement uncertainty intervals have a significant probability of being unrealistic, arising a high risk of the uncorrected clinical decision. " flow chart to the selection of models for the determination of measurement uncertainty in a medical laboratory is recommended.

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